Publication List

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Original Papers

    2023

  1. Taniue K, Oda T, Hayashi T, Kamoshida Y, Takeda Y, Sugawara A, Shimoura Y, Negishi L, Nagashima T, Okada-Hatakeyama M, Kawamura Y, Goshima N, Akimitsu N , and Akiyama T. (2023) LncRNA ZNNT1 induces p53 degradation by interfering with the interaction between p53 and the SART3-USP15 complex. PNAS Nexus. 2, pgad220
  2. Imura R, Kumikura Y, Yan L, Shimoura Y, Takahashi H, Isa H, Wada Y, and Akimitsu N . (2023) DOTA chelation through click chemistry enables favorable biodistribution of 89Zr-radiolabeled antibodies: A comparison with DFO chelation. Preprint
  3. Shima Y, Sasagawa S, Ota N, Oyama R, Tanaka M, Kubota-Sakashita M, Kawakami H, Kobayashi M, Takubo N, Ozeki AN, Sun X, Kim YJ, Kamatani Y, Matsuda K, Maejima K, Fujita M, Noda K, Kamiyama H, Tanikawa R, Nagane M, Shibahara J, Tanaka T, Rikitake Y, Mataga N, Takahashi S, Kosaki K, Okano H, Furihata T, Nakaki R, Akimitsu N. , Wada Y, Ohtsuka T, Kurihara H, Kamiguchi H, Okabe S, Nakafuku M, Kato T, Nakagawa H, Saito N, and Nakatomi H. (2023) Increased PDGFRB and NF-κB signaling caused by highly prevalent somatic mutations in intracranial aneurysms. Sci. Transl. Med. 15(700)

    4. 2022

  4. Kurosaki T, Mitsutomi S, Hewko A, Akimitsu N and Maquat LE. (2022) Integrative omics indicate FMRP sequesters mRNA from translation and deadenylation in human neuronal cells. Mol. Cell. 82, 4564–4581
  5. Shimizu D, Taniue K, Matsui Y, Haeno H, Araki H, Miura F, Fukunaga M, Shiraishi K, Miyamoto Y, Tsukamoto S, Komine A, Kobayashi Y, Kitagawa A, Yoshikawa Y, Sato K, Saito T, Ito S, Masuda T, Niida A, Suzuki M, Baba H, Ito T, Akimitsu N , Kodera Y, and Mimori K. (2022) Pan-cancer methylome analysis for cancer diagnosis and classification of cancer cell of origin. Cancer Gene Ther. 29, 428–436
  6. Taniue K, Tanu T, Shimoura Y, Mitsutomi S, Han H, Kakisaka R, Ono Y, Tamamura Y, Takahashi K, Wada Y, Mizukami Y, and Akimitsu N . (2022) RNA Exosome Component EXOSC4 Amplified in Multiple Cancer Types Is Required for the Cancer Cell Survival. Int. J. Mol. Sci. 23(1)496
  7. Jang J, Kumakura Y, Tatenuma K, Ozeki AN, Wada Y, Akimitsu N , Tsuguchi A, KIkunaga H, Higaki S, and Uesaka M. (2022) A preliminary biodistribution study of [99mTc] sodium pertechnetate prepared from an electron linear accelerator and activated carbon-based 99mTc generator. Nucl. Med. Biol. In press
  8. Imura R, Ozeki AN, Shida N, Kobayashi M, Ida H, Wada Y, Akimitsu N , and Kumakura Y. (2022) Radiolabeling of PSMA-617 with 89Zr: A novel use of DMSO to improve radiochemical yield and preliminary small-animal PET result. Nucl. Med. Biol.106–107, 21-28

    9. 2021

  9. Shimizu D, Taniue K, Matsui Y, Haeno H, Araki H, Miura F, Fukunaga M, Shiraishi K, Miyamoto Y, Shimokawa M, Tsukamoto S, Komine A, Kobayashi Y, Sato K, Saito T, Ito S, Masuda T, Niida A, Suzuki M, Baba H, Ito T, Akimitsu N. , Kodera Y, and Mimori K. (2021) “Pancancer Methylome Analysis for Cancer Diagnosis and Classification of Cancer Cell of Origin Cancer Gene Ther. In Press
  10. Tanu T, Taniue K, Imamura K, Onoguchi-Mizutani R, Han H, Jensen TH, and Akimitsu N. (2021) hnRNPH1-MTR4 complex-mediated regulation of NEAT1v2 stability is critical for IL8 expression. RNA Biol.1-11
  11. Yamamoto K, Goyama S, Asada S, Fujino T, Yonezawa T, Sato N, Takeda R, Tsuchiya A, Fukuyama T, Tanaka Y, Yokoyama A, Toya H, Kon A, Nannya Y, Onoguchi-Mizutani R, Nakagawa S, Hirose T, Ogawa S, Akimitsu N, Kitamura T. (2021) A histone modifier, ASXL1, interacts with NONO and is involved in paraspeckle formation in hematopoietic cells. Cell Rep. 36(8)109576
  12. Obata Y, Nakaue H, Hirasaki K, Akimitsu N, Yokoya A. (2021) Expression of an X-Ray Irradiated EGFP-Expressing Plasmid Transfected into Nonirradiated Human Cells. Radiat. Res. *196(3)261-271
  13. Shirahama S, Taniue K, Mitsutomi S, Tanaka R, Kaburaki T, Sato T, Takeuchi M, Kawashima H, Urade Y, Aihara M, Akimitsu N. (2021) Human U90926 orthologous long non-coding RNA as a novel biomarker for visual prognosis in herpes simplex virus type-1 induced acute retinal necrosis. Sci. Rep. 11(1)12164
  14. Onoguchi-Mizutani R, Kirikae Y, Ogura Y, Gutschner T, Diederichs S, Akimitsu N. (2021) Identification of a heat-inducible novel nuclear body containing the long noncoding RNA MALAT1. J Cell Sci. 134(10)jcs253559
  15. Hasegawa S, Inoue T, Nakamura Y, Fukaya D, Uni R, Wu CH, Fujii R, Peerapanyasut W, Taguchi A, Kohro T, Yamada S, Katagiri M, Ko T, Nomura S, Nakanishi Ozeki A, Susaki EA, Ueda HR, Akimitsu N, Wada Y, Komuro I, Nangaku M, Inagi R. (2021) Activation of Sympathetic Signaling in Macrophages Blocks Systemic Inflammation and Protects against Renal Ischemia-Reperfusion Injury. J Am. Soc. Nephrol. ASN2020121723
  16. Kurosaki T, Imamachi N, Pröschel C, Mitsutomi S, Nagao R, Akimitsu N, Maquat LE.(2021) Loss of the fragile X syndrome protein FMRP results in misregulation of nonsense-mediated mRNA decay. Nat. Cell Biol. 23(1)40-48
  17. Yeasmin F, Imamachi N, Tanu T, Taniue K, Kawamura T, Yada T, Akimitsu N. (2021) Identification and analysis of short open reading frames (sORFs) in the initially annotated noncoding RNA LINC00493 from human cells. J Biochem. 169(4)421-434
  18. Onoguchi-Mizutani R, Kishi Y, Ogura Y, Nishimura Y, Imamachi N, Suzuki Y, Miyazaki S, Akimitsu N. (2021) Identification of novel heat shock-induced long non-coding RNA in human cells. J Biochem.169(4)497-505

    19. 2020

  19. Uni R, Inoue T, Nakamura Y, Fukaya D, Hasegawa S, Wu CH, Fujii R, Surattichaiyakul B, Peerapanyasut W, Ozeki A, Akimitsu N. , Wada Y, Nangaku M, Inagi R.(2020) Vagus nerve stimulation even after injury ameliorates cisplatin-induced nephropathy via reducing macrophage infiltration. Sci Rep.10(1)9472
  20. Wakida H, Kawata K, Yamaji Y, Hattori E, Tsuchiya T, Wada Y, Ozaki H, Akimitsu N. (2020) Stability of RNA sequences derived from the coronavirus genome in human cells. Biochem Biophys Res Commun. 527(4)993-999
  21. Yamada T, Imamachi N, Imamura K, Taniue K, Kawamura T, Suzuki Y, Nagahama M, Akimitsu N. (2020) Systematic Analysis of Targets of Pumilio-Mediated mRNA Decay Reveals that PUM1 Repression by DNA Damage Activates Translesion Synthesis. Cell Rep. 31(5)107542
  22. Sun X, Kawata K, Miki A, Wada Y, Nagahama M, Takaya A, Akimitsu N. (2020) Exploration of Salmonella Effector Mutant Strains on MTR4 and RRP6 Degradation.Biosci Trends. 14(4)255-262
  23. Kawata K, Wakida H, Yamada T, Taniue K, Han H, Seki M, Suzuki Y, Akimitsu N. (2020) Metabolic labeling of RNA using multiple ribonucleoside analogs enables simultaneous evaluation of transcription and degradation rates. Genome Res. 30(10)1481-1491

    24. 2019

  24. Mitsutomi S, Akimitsu N, Sekimizu K, Kaito C. (2019) Identification of 2H phosphoesterase superfamily proteins with 2'-CPDase activity. Biochimie.

    25. 2018

  25. Nakaue H, Obata Y, Kaminaga K, Akimitsu N, Yokoya A. (2018) VISUALIZATION OF THE DNA REPAIR PROCESS IN MAMMALIAN CELLS TRANSFECTED WITH EGFP-EXPRESSING PLASMID DNA AFTER EXPOSURE TO X-RAYS IN VITRO. Radiat Prot Dosimetry.
  26. Kami D, Kitani T, Nakamura A, Wakui N, Mizutani R, Ohue M, Kametani F, Akimitsu N, Gojo S. (2018) The DEAD-box RNA-binding protein DDX6 regulates parental RNA decay for cellular reprogramming to pluripotency. PLoS One. 13(10)e0203708
  27. Imamura K, Takaya A, Ishida YI, Fukuoka Y, Taya T, Nakaki R, Kakeda M, Imamachi N, Sato A, Yamada T, Onoguchi-Mizutani R, Akizuki G, Tanu T, Tao K, Miyao S, Suzuki Y, Nagahama M, Yamamoto T, Jensen TH, Akimitsu N. (2018) Diminished nuclear RNA decay upon Salmonella infection upregulates antibacterial noncoding RNAs. EMBO J. 37(13)e97723
  28. Tano K, Onoguchi-Mizutani R, Yeasmin F, Uchiumi F, Suzuki Y, Yada T, Akimitsu N. (2018) Identification of Minimal p53 Promoter Region Regulated by MALAT1 in Human Lung Adenocarcinoma Cells. Front Genet. 8:208
  29. Yamada T, Imamachi N, Onoguchi-Mizutani R, Imamura K, Suzuki Y, Akimitsu N. (2018) 5'-Bromouridine IP Chase (BRIC)-Seq to Determine RNA Half-Lives. Methods Mol Biol. 1720:1-13

    30. 2017

  30. Hermawan I, Furuta A, Higashi M, Fujita Y, Akimitsu N, Yamashita A, Moriishi K, Tsuneda S, Tani H, Nakakoshi M, Tsubuki M, Sekiguchi Y, Noda N, Tanaka J. (2017) Four Aromatic Sulfates with an Inhibitory Effect against HCV NS3 Helicase from the Crinoid Alloeocomatella polycladia. Genome Res. 15(4)
  31. Okada T, Kurabayashi A, Akimitsu N, Furihata M. (2017) Expression of Cadherin-17 Promotes Metastasis in a Highly Bone Marrow Metastatic Murine Breast Cancer Model. Biomed Res Int. 2017:8494286
  32. Imamachi N, Salam KA, Suzuki Y, Akimitsu N. (2017) A GC-rich sequence feature in the 3' UTR directs UPF1-dependent mRNA decay in mammalian cells. Genome Res. 27(3):407-418

    33. 2016

  33. Xia J, Inagaki Y, Sawakami T, Song P, Cai Y, Hasegawa K, Sakamoto Y, Akimitsu N, Tang W and Kokudo N. (2016) Preliminary investigation of five novel long non-coding RNAs in hepatocellular carcinoma cell lines. Biosci Trends. 10(4):315-9.
  34. Katsura M, Cyou-Nakamine H, Zen Q, Zen Y, Nansai H, Amagasa S, Kanki Y, Inoue T, Kaneki K, Taguchi A, Kobayashi M, Kaji T, Kodama T, Miyagawa K, Wada Y, Akimitsu N and Sone H. (2016) Effects of Chronic Low-Dose Radiation on Human Neural Progenitor Cells. Sci Rep. 6.20027.
  35. Mizutani R, Imamachi N, Suzuki Y, Yoshida H, Tochigi N, Oonishi T, Suzuki Y and Akimitsu N, (2016) Oncofetal protein IGF2BP3 facilitates the activity of proto-oncogene protein eIF4E through the destabilization of EIF4E-BP2 mRNA. Oncogene. 35(27):3495-502.

    36. 2015

  36. Furuta A, Tsubuki M, Endoh M, Miyamoto T, Tanaka J, Salam KA, Akimitsu N, Tani H, Yamashita A, Moriishi K, Nakakoshi M, Sekiguchi Y, Tsuneda S, Noda N. (2015) Identification of Hydroxyanthraquinones as Novel Inhibitors of Hepatitis C Virus NS3 Helicase. Int J Mol Sci. 16(8).18439-53.
  37. Maekawa S, Imamachi N, Irie T, Tani H, Matsumoto K, Mizutani R, Imamura K, Kakeda M, Yada T, Sugano S, Suzuki Y, Akimitsu N (2015) Analysis of RNA decay factor mediated RNA stability contributions on RNA abundance. BMC Genomics. 16.154.
  38. Furuta A, Salam KA, Tani H, Tsuneda S, Sekiguchi Y, Akimitsu N, Noda N. (2015) A fluorescence-based screening assay for identification of hepatitis C virus NS3 helicase inhibitors and characterization of their inhibitory mechanism. Methods Mol Biol. 1259.211-28.
  39. Tani H, Imamachi N, Mizutani R, Imamura K, Kwon Y, Miyazaki S, Maekawa S, Suzuki Y, Akimitsu N (2015) Genome-wide analysis of long noncoding RNA turnover. Methods Mol Biol. 1262.305-20.

    40. 2014

  40. Salam KA, Furuta A, Noda N, Tsuneda S, Sekiguchi Y, Yamashita A, Moriishi K, Nakakoshi M, Tani H, Roy SR, Tanaka J, Tsubuki M, Akimitsu N (2014) PBDE :structure-activity studies for the inhibition of hepatitis C virus NS3 helicase. Molecules. 19(4).4006-20.
  41. Imamura K, Imamachi N, Akizuki G, Kumakura M, Kawaguchi A, Nagata K, Kato A, Kawaguchi Y, Sato H, Yoneda M, Kai C, Yada T, Suzuki Y, Yamada T, Ozawa T, Kaneki K, Inoue T, Kobayashi M, Kodama T, Wada Y, Sekimizu K and Akimitsu N. (2014) Long Noncoding RNA NEAT1-Dependent SFPQ Relocation from Promoter Region to Paraspeckle Mediates IL8 Expression upon Immune Stimuli.Mol Cell., 53(3), 393-406.
  42. Furuta A, Salam KA, Hermawan I, Akimitsu N., Tanaka J, Tani H, Yamashita A, Moriishi K, Nakakoshi M, Tsubuki M, Peng PW, Suzuki Y, Yamamoto N, Sekiguchi Y, Tsuneda S and Noda N (2014) Identification and biochemical characterization of halisulfate 3 and suvanine as novel inhibitors of hepatitis C virus NS3 helicase from a marine sponge. Mar Drugs. 12(1):462-76.

    43. 2013

  43. Imamachi N., Tani H., Mizutani R., Imamura K., Irie T., Suzuki Y. and Akimitsu N. (2013) BRIC-seq: a genome-wide approach for determining RNA stability in mammalian cells, Methods, 67(1):55-63
  44. Furuta A, Salam KA, Akimitsu N. Tanaka J, Tani H, Yamashita A, Moriishi K, Nakakoshi M, Tsubuki M, Sekiguchi Y, Tsuneda S, Noda N. (2013) Cholesterol sulfate as a potential inhibitor of hepatitis C virus NS3 helicase., J. Enzyme Inhib. Med. Chem., 29(2):223-9
  45. Tani T., Torimura M. and Akimitsu N., (2013) The RNA degradation pathway regulates the function of GAS5 a non-coding RNA in mammalian cells, PLoS ONE., 8(1):e55684.
  46. Salam KA., Furuta A., Noda N., Tsuneda S., Sekiguchi Y., Yamashita A., Moriishi K., Nakakoshi M., Tsubuki M., Tani H., Tanaka J. and Akimitsu N., (2013)Psammaplin A inhibits hepatitis C virus NS3 helicase, J. Nat. Med., 67(4):765-72.
  47. Tani H., Imamachi N., Salam KA., Mizutani R., Ijiri K., Irie T., Yada T., Suzuki Y., and Akimitsu N., (2013) Identification of hundreds of novel UPF1 target transcripts by direct determining whole transcriptome stability in mammalian cells, RNA Biology, 9, (11):1370-1379.

    48. - 2012

  48. Fujimoto Y., Salam KA., Furuta A., Matsuda Y., Fujita O., Tani H., Ikeda M., Kato N., Sakamoto N., Maekawa S., Enomoto N., de Voogd NJ., Nakakoshi M., Tsubuki M., Sekiguchi Y., Tsuneda S., Akimitsu N., Noda N., Yamashita A., Tanaka J. and Moriishi K., (2012) Inhibition of both protease and helicase activities of hepatitis C virus NS3 by an ethyl acetate extract of marine spongeAmphimedon sp., PLoS ONE, 7, (11):e48685.
  49. Tani H., Mizutani R., Salam KA. Tano K., Ijiri K., Wakamatsu A., Isogai T., Suzuki Y. and Akimitsu N., (2012) Genome-wide determination of RNA stability reveals hundreds of short-lived non-coding transcripts in mammals, Genome Res., 22, 947-956.
  50. Miyagawa R., Tano K., Mizuno R., Nakamura Y., Ijiri K., Rakwal R., Shibato J., Masuo Y., Mayeda A., Hirose T. and Akimitsu N., (2012) Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles., RNA., 18, 738-751.
  51. Mizutani R., Wakamatsu A., Tanaka N., Yoshida H., Tochigi N., Suzuki Y., Oonishi T., Tani H., Tano K., Ijiri K., Isogai T. and Akimitsu N., (2012) Identification and characterization of novel genotoxic stress-inducible nuclear long noncoding RNAs in mammalian cells., PLoS ONE, 7: e34949.
  52. Yamashita A., Salam KA., Furuta A., Matsuda Y., Fujita O., Tani H., Fujita Y., Fujimoto Y., Ikeda M., Kato N., Sakamoto N., Maekawa S., Enomoto N., Nakakoshi M., Tsubuki M., Sekiguchi Y., Tsuneda S., Akimitsu N., Noda N., Tanaka J., Moriishi K., (2012) Inhibition of hepatitis C virus replication and viral helicase by ethyl acetate extract of the marine feather star Alloeocomatella polycladia., Marine Drugs, 10, 744-761.
  53. Salam KA., Furuta A., Noda N., Tsuneda S., Sekiguchi Y., Yamashita A., Moriishi K., Nakakoshi M., Tsubuki M., Tani H., Tanaka J. and Akimitsu N.(2012) Inhibition of hepatitis C virus NS3 helicase by Manoalide., J. Nat. Prod., 75, 650-654.
  54. Tano K., Mizuno R., Okada T., Rakwal R., Shibato J., Masuo Y., Ijiri K.Akimitsu N.　(2010) MALAT-1 enhances cell motility of lung adenocarcinoma cells by influencing the expression of motility-related genes., FEBS letters. 584, 4575-4580.
  55. Tani H., Nakamura Y., Ijiri K. and Akimitsu N.(2010) Stability of MALAT-1, a nuclear long non-coding RNA in mammalian cells, varies in various cancer cells., Drug Discov. Ther., 4, 235-239.
  56. Tano K., Hamamoto H., Ito T., Sumiya E., Rakwal R., Shibato J., Masuo Y., Ijiri K., Sekimizu K. and Akimitsu N.(2010) Reduced expression of Sytl 1 and Ccdc21 and impaired induction of Mt I by oxidative stress in SII-K1 knockout mice., Drug Discov. Ther., 4, 368-372.
  57. Tani H., Fujita O., Furuta A., Matsuda Y., Miyata R., Akimitsu N., Tanaka J., Tsuneda S., Sekiguchi Y. and Noda N., (2010) Real-time monitoring of RNA helicase activity using fluorescence resonance energy transfer in vitro., Biochem. Biophys. Res. Commun., 393, 131-136.
  58. Tani H., Akimitsu N., Fujita O., Matsuda Y., Miyata R., Tsuneda S., Igarashi M., Sekiguchi Y. and Noda N., (2009)High-throughput screening assay of hepatitis C virus helicase inhibitors using fluorescence-quenching phenomenon., Biochem. Biophys. Res. Commun. 379, 1054-1059.
  59. Takahashi M., Furihata M., Akimitsu N., Watanabe M., Kaul S., Yumoto N., and Okada T., (2008) A highly bone marrow metastatic murine breast cancer model established through in vivo selection exhibits enhanced anchorage-independent growth and cell migration mediated by ICAM-1., Clin. Exp. Metastasis, 25, 517-529.
  60. Akimitsu N., Tanaka J., and Pelletier J., (2007) Translation of nonSTOP mRNA is repressed post-initiation in mammalian cells., EMBO J., 26, 2327-2338.
  61. Takabatake N., Okamura M., Yokoyama N., Ikehara Y., Akimitsu N., Arimitsu N., Hamamoto H., Sekimizu K., Suzuki H., andIgarashiI., (2007) Glycophorin A-knockout mice, which lost sialoglycoproteins from the red blood cell membrane, are resistant to lethal infection of Babesia rodhaini., Vet. Parasitol., 148, 93-101.
  62. Ito T., Arimitsu N., Takeuchi M., Kawamura N., Nagata M., Saso K., Akimitsu N., Hamamoto H., Natori S., Miyajima A., and Sekimizu K., (2006) Transcription elongation factor S-II is required for definitive hematopoiesis., Mol. Cell. Biol., 26, 3194-3203.
  63. Aramaki Y., Ogawa K., Toh Y., Ito T., Akimitsu N., Hamamoto H., Sekimizu K., Matsusue K., Kono A., Iguchi H., and Takiguchi S., (2005) Direct interaction between metastasis-associated protein 1 and endophilin 3., FEBS Lett.579, 3731-3736.
  64. Rungruang M., Kaneko O., Murakami Y., Tsuboi T., Hamamoto H., Akimitsu N., Sekimizu K., Kinoshita T., and Torii T., (2005) Erythrocyte surface glycosylphosphatidyl inositol anchored receptor for the malaria parasite., Mol. Biochem. Parasitol., 140, 13-21.
  65. Akimitsu N., KimH-S., HamamotoH., KamuraK., Fukuma N., ArimitsuN., Ono K., Wataya Y., Torii M. and Sekimizu K., (2004)Duffy antigen is important for lethality of the lethal strainP.yoelii17XL., Parasitol. Res., 93, 499-503.
  66. Ishida T.#, Akimitsu N.#, Kashioka T.#, Hatano M.#, Kubota T., Ogata Y., Sekimizu K., and Katayama T., (2004) DiaA, a novel DnaA-binding protein, ensures the timely initiation of Escherichia coli chromosome replication., J. Biol. Chem., 279, 45546-45555.
    #:equal contribution
  67. Hossain MS., Kurokawa K., Akimitsu N., and Sekimizu K., (2004) DNA topoisomerase II is required for the G0-to-S phase transition in Drosophila Schneider cells, but not in yeast.Genes Cells., 9, 905-917.
  68. Jilma B., Akimitsu N., Fukuma N., Sekimizu K., and Jilma-Stohlawetz P., (2004) Man, mouse and Duffy genotype-phenotype-specific pharmacokinetics of monocyte chemotactic protein-1., Transfus. Med., 14, 251-252.
  69. Akimitsu N., Kamura K., Tone S., Sakaguchi A., Kikuchi A., Hamamoto H. and Sekimizu K., (2003) Induction of apoptosis by depletion of DNA topoisomerase IIalpha in mammalian cells., Biochem. Biophys. Res. Commun., 307, 301-307.
  70. Kashiwazaki M., Tanaka T., Kanda H., Ebisuno Y., Izawa D., Fukuma N., Akimitsu N., Sekimizu K., Monden M. and Miyasaka M., (2003) A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions., Int. Immunol., 15, 1219-1227.
  71. Arimitsu N., Akimitsu N., Kotani N., Takasaki S., Kina T., Hamamoto H., Kamura K. and Sekimizu K., (2003) Glycophorin A requirement for expression of O-linked antigens on the erythrocyte membrane., Genes Cells., 8, 769-777.
  72. Hossain MS., Akimitsu N., Kurokawa K. and Sekimizu K., (2003) Myogenic differentiation of Drosophila Schneider cells by DNA double-strand break-inducing drugs., Differentiation, 71, 271-280.
  73. Fukuma N., Akimitsu N., Hamamoto H., Kusuhara H., Sugiyama Y. and Sekimizu K., (2003) A role of the Duffy antigen for the maintenance of plasma chemokine concentrations., Biochem. Biophys. Res. Commun., 303, 137-139.
  74. Akimitsu N., Adachi N., Hirai H., Hossain MS., Hamamoto H., Kobayashi M., Aratani Y., Koyama H. and Sekimizu K., (2002) Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha., Genes Cells., 8, 393-402.
  75. Kaito C., Akimitsu N., Watanabe H. and Sekimizu K., (2002) Silkworm larvae as an animal model of bacterial infection pathogenic to humans., Microb. Pathog., 32, 183-190.
  76. Koyanagi-Katsuta R., Akimitsu N., Hamamoto H., Arimitsu N., Hatano T. and Sekimizu K., (2002) Embryonic lethality of mutant mice deficient in the p116 gene., J. Biochem., 131, 833-837.
  77. Kaito C., Kurokawa K., Hossain MS., Akimitsu N.and Sekimizu K., (2002) Isolation and characterization of temperature-sensitive mutants of the Staphylococcus aureus dnaC gene., FEMS Microbiol. Lett., 210, 157-164.
  78. Hossain MS., Akimitsu N., Takaki T., Hirai H. and Sekimizu K., (2002) ICRF-193, a catalytic inhibitor of DNA topoisomerase II, inhibits re-entry into the cell division cycle from quiescent state in mammalian cells., Genes Cells, 7, 285-295.
  79. Inoue R., Kaito C., Tanabe M., Kamura K., Akimitsu N.and Sekimizu K., (2001) Genetic identification of two distinct DNA polymerases, DnaE and PolC, that are essential for chromosomal DNA replication in Staphylococcus aureus., Mol. Genet. Genomics, 266, 564-571.
  80. Koyanagi-Katsuta R., Akimitsu N., Arimitsu N., Hatano T., and Sekimizu K., (2000) Apoptosis of mouse embryonic stem cells induced by single cell suspension., Tissue Cell, 32, 66-70.
  81. Akimitsu N., Hamamoto H., Inoue R., Shoji M., Akamine A., Takemori K., Hamasaki N., and Sekimizu K., (1999) Increase in resistance of methicillin-resistant Staphylococcus aureus to beta-lactams caused by mutations conferring resistance to benzalkonium chloride, a disinfectant widely used in hospitals., Antimicrob. Agents Chemother., 43, 3042-3043.
  82. Ohba A., Inoue R., Akimitsu N., Mizushima T., and Sekimizu K., (1998) Identification of proteins whose amounts are altered by mutation in the pgsA gene of Escherichia coli., Biol. Pharm. Bull., 21, 1139-1141.
  83. Katayama T.#, Akimitsu N.#, Mizushima T., Miki T., and Sekimizu K., (1997) Overinitiation of chromosome replication in the Escherichia coli dnaAcos mutant depends on activation of oriC function by the dam gene product., Mol. Microbiol., 25, 661-670.
    #: equal contribution
  84. Katayama T., Kubota T., Takata M., Akimitsu N., and Sekimizu K., (1996) Disruption of the hslU gene, which encodes an ATPase subunit of the eukaryotic 26S proteasome homolog in Escherichia coli, suppresses the temperature-sensitive dnaA46 mutation., Biochem. Biophys. Res. Commun., 229, 219-224.
  85. Akimitsu N., Mizushima T., Suzuki E., Miki T., Sekimizu K., (1996) Growth phenotypes of Escherichia coli carrying a mutation of acidic phospholipid synthesis., Biol. Pharm. Bull., 19, 1275-1278.

Reviews

【英文総説：Review articles written in English】

    2023

  1. Taniue K, and Akimitsu N . (2023) The Hidden Layer of RNA Variants. RNA Structure and Function. 343–369
  2. Akimitsu N . (2023) Chapter 10 - Techniques for Analyzing Genome-wide Expression of Non-coding RNA Handbook of Epigenetics (3rd Edition) The New Molecular and Medical Genetics. 163-184
  3. Basso J, Fortuna A, Vitorino R, and Akimitsu N , and Vitorino C. (2023) Chapter 20 - Non-coding RNAs in glioblastoma at a glance. New Insights Into Glioblastoma, Diagnosis, Therapeutics and Theranostics. 477-504
  4. Onoguchi-Mizutani R, Akimitsu N. (2022) Long noncoding RNA and phase separation in cellular stress response. J. Biochem. 171(3)269-276
  5. Taniue K, Akimitsu N. (2021) Aberrant phase separation and cancer. FEBS J.
  6. Taniue K, Akimitsu N. (2021) Fusion Genes and RNAs in Cancer Development. RNA. 7(1):10
  7. Vitorino R, Guedes S, Amado F, Santos M, Akimitsu N. (2021) The role of micropeptides in biology. Cell Mol Life Sci. 78(7)3285-3298
  8. K Kawata, Akimitsu N. (2021) Regulation of RNA Stability Through RNA Modification. Epitranscriptomics. pp.217-246
  9. Taniue K, Akimitsu N. (2021) The Functions and Unique Features of LncRNAs in Cancer Development and Tumorigenesis. Int J Mol Sci. 22(2)632
  10. Shirahama S, Miki A, Kaburaki T, Akimitsu N.(2020) Long Non-coding RNAs Involved in Pathogenic Infection. Frontiers in Genetics.
  11. Yamada T, Akimitsu N. (2019) Contributions of regulated transcription and mRNA decay to the dynamics of gene expression. Wiley Interdiscip Rev RNA. 10(1)e1508.
  12. Yeasmin F, Yada T, Akimitsu N. (2018) Micropeptides Encoded in Transcripts Previously Identified as Long Noncoding RNAs: A New Chapter in Transcriptomics and Proteomics.Front Genet. 25(9)144.
  13. Imamura K, Akimitsu N. (2014) Long Non-Coding RNAs Involved in Immune Responses.Front Immunol. 13;5:573.
  14. Salam KA, Akimitsu N. (2013) Hepatitis C virus NS3 inhibitors: current and future perspectives. Biomed Res Int. 2013:467869.
  15. Imamachi N., Tani H. and Akimitsu N. (2012) Up-frameshift protein 1 (UPF1): Multitalented entertainer in RNA decay., Drug Discoveries and Therapeutics, 6, 55-61.
  16. Tano K. and Akimitsu N., (2012) Long Non-coding RNAs In Cancer Progression, Frontiers in Genetics, 3:219.
  17. Tani T. and Akimitsu N., (2012) Genome-wide technology for determination of RNA stability in mammalian cells: Historical perspective and recent advantages based on modified nucleotide labeling, RNA Biology, 9(10):1233-8.
  18. Hamamoto H., Akimitsu N., Arimitsu N. and Sekimizu K., (2008) Role of the Duffy antigen and glycophorin A in malaria infection and erythrocyte. Drug Discoveries and Therapeutics, 2, 58-63.
  19. Tano K., Nagata M. and Akimitsu N. (2008) S-II mediated gene regulation. Drug Discoveries and Therapeutics, 2, 136-139.
  20. Akimitsu N., (2008) Messenger RNA surveillance systems monitoring proper translation termination., J. Biochem., 143, 1-8.
  21. Hamamoto H., Akimitsu N., Arimitsu N. and Sekimizu K., (2008) Role of the Duffy antigen and glycophorin A in malaria infection and erythrocyte. Drug Discoveries and Therapeutics, 2, 58-63.

【日本語総説・解説・紀要等】

  1. 韓晗、川田健太郎、山田俊理、谷上賢瑞、秋光信佳、（2020）スプライシングアイソフォームと修飾塩基の解析、遺伝子医学、メディカル ドゥ、33
  2. 水谷 玲菜、秋光信佳、（2016）　RNA結合タンパク質IMP3は標的mRNA分解を介してがん原遺伝子eIF4Eの活性を促進する、実験医学 2016年5月号 vol.34 No.8 pp1289-1292
  3. 秋光信佳 監修、（2015）　長鎖ノンコーディングRNA 遺伝子発現制御メカニズム別・機能リファレンス、細胞工学 2015年1月号
  4. 秋光信佳、（2013）　福島原発事後の復興に向けた今日までの進捗状況、薬事日報、3月号特集号
  5. 秋光信佳、（2013）　RNAダイナミクスから迫る生命現象、薬事日報、3月特集号
  6. 秋光信佳、（2012）　ゲノムワイドなRNA分解測定、細胞工学別冊「次世代シークエンサー　目的別アドバンストメソッド」、100-108.
  7. 秋光信佳、（2012）　ノンコーディングRNAから理解する「がん」のメカニズム、科学フォーラム、338、36-39.
  8. 秋光信佳、（2012）　核内構造とエピジェネティック制御をつなぐ核内長鎖ノンコーディングRNA、細胞工学、31、917-922
  9. 谷英典、水谷玲菜、鈴木穣、秋光信佳、（2012）　RNAの安定性を指標にして機能不明な長鎖ノンコーディングRNAの性質を定義する、細胞工学、31、926-927.
  10. 秋光信佳、（2012）　福島第一原発事故への取り組み、実験医学、30、462-463.
  11. 秋光信佳、藤井紳一郎、藤井健太郎、月本光俊、小島周二、（2011）軟Ｘ線によるアデノシン三リン酸（ＡＴＰ）放射線障害の生物学的評価、JAEA-Review, 031, 7-12.
  12. 秋光信佳, (2011) 機能性ノンコーディングRNAによる核内遺伝子発現の制御 東京理科大学科学フォーラムRNA科学の新たな展開, 323, 28-31
  13. 秋光信佳、（2011）核内長鎖ncRNAによるスプライシング・転写制御、実験医学, 29、 1743-1748.
  14. 秋光信佳、（2011）機能性ノンコーディングRNAによる核内遺伝子発現の制御、科学フォーラム、323、28-31.
  15. 秋光信佳、（2010）、RNA研究の最前線：RNA動態制御の分子基盤から創薬応用まで、薬事日報、3月特集号
  16. 秋光信佳、（2007）、哺乳動物細胞の異常メッセンジャーRNAサーベイランス機構-終止コドン欠失型mRNA（ノンストップmRNA）の翻訳抑制現象、実験医学、25、1845-1849.

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